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Figures on the impact of the pandemic on health in the Region of Madrid (Comunidad de Madrid) stand well above those in other regions in Spain both in absolute and relative terms. This section does not seek to compare Madrid to any other region in the country. However, this ‘metropolitan’ region is rather peculiar from a socioeconomic point of view and some geographical aspects shall therefore be taken into account, e.g. it shows a high population density; the fourth busiest airport in the European Union is located in the Region, what entails a significant flow of national, European and international passengers; the fact that it is the central hub for the main road and rail networks in Spain; the economic dynamism; the sociodemographic and cultural diversity, etc.
[[File:Logo MonografíaMadrid COVID--19-cases-in-the-Region-of-Madrid 2020 map 17918 eng.jpg||left|thumb|300px|Map: COVID-19 cases in the region of Madrid. 2020. Madrid. [//centrodedescargas.cnig.es/CentroDescargas/busquedaRedirigida.do?ruta=PUBLICACION_CNIG_DATOS_VARIOS/aneTematico/Europa_DensidadMadrid_COVID--de19-poblacioncases-enin-the-laRegion-Unionof-Europea_2019_mapa_18193_spaMadrid_2020_map_17918_eng.pdf PDF]. [//centrodedescargas.cnig.es/CentroDescargas/busquedaRedirigida.do?ruta=PUBLICACION_CNIG_DATOS_VARIOS/aneTematico/Europa_DensidadMadrid_Casos-de-poblacionCOVID--19-en-la-UnionComunidad-Europea_2019_mapa_18193_spade-Madrid_2020_mapa_17918_spa.zip DatosMore information].]][[File:Logo MonografíaSpain Population-over-65-years-of-age-in-the-Region-of-Madrid 2020 map 18138 eng.jpg||left|thumb|300px|Map: Population over 65 years of age in the region of Madrid. 2020. Madrid.[//centrodedescargas.cnig.es/CentroDescargas/busquedaRedirigida.do?ruta=PUBLICACION_CNIG_DATOS_VARIOS/aneTematico/Europa_DensidadSpain_Population-over-de65-years-of-age-poblacionin-enthe-laRegion-Unionof-Europea_2019_mapa_18193_spaMadrid_2020_map_18138_eng.pdf PDF]. [//centrodedescargas.cnig.es/CentroDescargas/busquedaRedirigida.do?ruta=PUBLICACION_CNIG_DATOS_VARIOS/aneTematico/Europa_DensidadEspana_Poblacion-mayor-de-poblacion65-anos-en-la-UnionComunidad-de-Europea_2019_mapa_18193_spaMadrid_2020_mapa_18138_spa.zip DatosMore information].]]Coronavirus peaked in Madrid some time earlier than in the rest of the country. Both the city of Madrid and the Region of Madrid (Comunidad de Madrid) reached the peak of COVID-19 cases and deaths during the last days of March 2020, whilst most of the other regions in Spain peaked well into early April or even later. 12,517 people died in Madrid in the month of March 2020 (considering all causes), whilst 4,195 deaths were recorded during the same month of the previous year (National Statistics Institute, 2020 and 2021). Furthermore, the fall in numbers after peaking was slower and more gradual than in other regions in the country.
Indicators show unevenly distributed figures when comparing the city of Madrid to the Region of Madrid (Comunidad de Madrid). There are ample differences between the different boroughs and municipalities as well as by sex and by age. The age distribution of the 8,747 people who died from COVID-19 in the period comprising the first wave of the pandemic shows that nearly 83% (7,252) were over 70 years of age (ISCIII, 2021). When broken down by sex, statistics show that 58% of dead were men and 42% were women. It shall also be noted that this difference by sex was larger in the 40 to 69-years-of-age group, in which 1,034 dead were men (71%) and 418 were women (29%). By contrast, this difference by sex nearly disappeared in the under 39-years-of-age group, in which 22 men and 21 women passed away.