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The second trip to the Indies had a colonising purpose. They were up to 21 ships and 2,500 pioneers: soldiers, friars, merchants, artisans, supplies, farm animals, etc. Juan de la Cosa, Ponce de León, Father Las Casas were all travelling when Columbus was sailing on his third voyage and widespread explorations of the islands and the coasts were already taking place. Balboa confirms that there is another ocean to the west. It is a new continent, with unknown flora and fauna, unimaginable cultures and fabulous empires, whose mythology predicted the arrival of mysterious gods from the sea.<br>

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[[File:North-Atlantic_Columbus-voyages-and-contemporary-explorations_1492-1504_map_17064_eng.jpg|left|thumb|300px|Map: Columbus voyages and contemporary explorations. 1492-1504. North Atlantic. [//centrodedescargas.cnig.es/CentroDescargas/busquedaRedirigida.do?ruta=PUBLICACION_CNIG_DATOS_VARIOS/aneTematico/North-Atlantic_Columbus-voyages-and-contemporary-explorations_1492-1504_map_17064_eng.pdf PDF]. [//centrodedescargas.cnig.es/CentroDescargas/busquedaRedirigida.do?ruta=PUBLICACION_CNIG_DATOS_VARIOS/aneTematico/North-Atlantic_Columbus-voyages-and-contemporary-explorations_1492-1504_map_17064_eng.zip Data].]]

America was the discovery of an unexpected and prodigious reality, which Spain had to tackle. The original peoples of the new continent also had to face the discovery of a “western culture” (oriental for them) in its Hispanic interpretation. For them it was, equally, an unthinkable and prodigious scenario. Both existences accepted their common challenge with the mindset and the instruments that were available at that time.<br>