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'''COPD'''
[[File:Logo MonografíaSpain_Reported-prevalence-of-COPD-in-the-population-over-15-years-of-age_2017_map_17860_eng.jpg|left|thumb|300px|Map: Reportered Reported prevalence of COPD in the population over 15 years of age. 2017. Spain . [//centrodedescargas.cnig.es/CentroDescargas/busquedaRedirigida.do?ruta=PUBLICACION_CNIG_DATOS_VARIOS/aneTematico/Espana_PrevalenciaSpain_Reported-prevalence-of-deCOPD-obesidadin-enthe-lapopulation-poblacionover-mayor15-deyears-18of-anos_2017_mapa_17861_spaage_2017_map_17860_eng.pdf PDF]. [//centrodedescargas.cnig.es/CentroDescargas/busquedaRedirigida.do?ruta=PUBLICACION_CNIG_DATOS_VARIOS/aneTematico/Espana_PrevalenciaSpain_Reported-deprevalence-obesidadof-enCOPD-in-the-lapopulation-poblacionover-mayor15-deyears-18of-anos_2017_mapa_17861_spaage_2017_map_17860_eng.zip Data]. Interactive versions [//interactivo-atlasnacional.ign.es/index.php#c=indicator&i=r_122_tc12329.r_122_tc12329&st=TotalA02&view=map10 1] [//interactivo-atlasnacional.ign.es/index.php#c=indicator&i=c12328.c12328&t=A02&view=map10 Versión interactiva2] [//interactivo-atlasnacional.ign. es/index.php#c=indicator&i=c12327.c12327&t=A02&view=map10 3]. ]]
Chronic Obstructive Pulmonary Disease (COPD) does not appear to be a predisposing factor for SARS-CoV-2 infection. However, once infection occurs and the disease develops, there is an increased risk of hospital admission, admission to intensive care unit (ICU) and death. Furthermore, the respiratory symptoms of COVID-19 may sometimes be confused with COPD exacerbations, which may delay diagnosis and affect the clinical course. The underlying pathophysiological mechanism would be an increased expression of ACE2 receptors (to which the virus binds to penetrate the cell) in the bronchial epithelium, amongst others.